Publications

1. Jay L. Duffner, Paul A. Clemons, Angela N. Koehler. "A Pipeline for Ligand Discovery Using Small Molecule Microarrays." Curr. Opin. Chem. Biol. Accepted, November 2006.

2. Thomas J. F. Nieland, Jared T. Shaw, Firoz A. Jaipuri, Zoltan Maliga, Jay L. Duffner, Angela N. Koehler, Monty Krieger. "The Influence of Clinical and Experimental HDL-Cholesterol Elevating Drugs on the Activity of the HDL Receptor SR-BI." Submitted, October 2006.

3. Hua Miao, John Tallarico, Hiroyuki Hayakawa, Karl Münger, Jay L. Duffner, Angela N. Koehler, Stuart L. Schreiber, Timothy A. Lewis. "Ring-Opening and Ring-Closing Reactions of a Shikimic Acid-Derived Substrate Leading to Diverse Small Molecules." Accepted, October 2006.

4. James E. Bradner, Olivia M. McPherson, Angela N. Koehler. "A Method for the Covalent Capture and Screening of Diverse Small Molecules in a Microarray Format." Nature Protocols, Accepted, September 2006.

5. Nicola Tolliday, Paul A. Clemons, Paul Ferraiolo, Angela N. Koehler, Timothy A. Lewis, Xiaohua Li, Stuart L. Schreiber, Daniela S. Gerhard, Scott Eliasof. "Small Molecules, Big Players: The National Cancer Institute’s Initiative for Chemical Genetics." Cancer Res. 66, 1-8, 2006. (cover image)

6. James E. Bradner, Olivia M. McPherson, Ralph Mazitschek, David Barnes-Seeman, John P. Shen, Jasmeet Dhaliwal, Jay L. Duffner, Kristen E. Stevenson, Seung Bum Park, Donna S. Neuberg, Paul Nghiem, Stuart L. Schreiber, Angela N. Koehler. "A Robust Small-Molecule Microarray Platform for Screening Cell Lysates." Chem. Biol. 13, 493-504, 2006.
* This article was featured in the Research Highlights section of Nature Biotechnology, 24, 799, 2006.

7. David Barnes-Seeman, Seung Bum Park, Angela N. Koehler, Stuart L. Schreiber. "Expanding the Functional Group Compatibility of Small-Molecule Microarrays: Discovery of Novel Calmodulin Ligands."Angew. Chem. Int. Ed. 42, 2376-2379, 2003 (cover image).

8. Angela N. Koehler, Alykhan F. Shamji, Stuart L. Schreiber. "Discovery of an Inhibitor of a Transcription Factor Using Small Molecule Microarrays and Diversity-Oriented Synthesis."J. Am. Chem. Soc. 125, 8420-8421, 2003.

9. Paul A. Clemons, Angela N. Koehler, Bridget K. Wagner, Timothy G. Sprigings, David R. Spring, Randall W. King, Stuart L. Schreiber, Michael A. Foley. "A One Bead, One Stock Solution Approach to Chemical Genetics: Part 2."Chem. Biol. 8, 1183-1195, 2001.

10. Gavin MacBeath, Angela N. Koehler, Stuart L. Schreiber. "Printing Small Molecules Onto Microarrays and Detecting Protein-Ligand Interactions en Masse."J. Am. Chem. Soc. 121, 7697-7698, 1999.

11. Arthur Glasfeld, Angela N. Koehler, Maria A. Schumacher, Richard G. Brennan. "The Role of Lysine 55 in Determining the Specificity of the Purine Repressor for its Operators through Minor Groove Interactions."J. Mol. Biol. 291, 347-361, 1999.