Current Members
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| principal investigator |
Contact
email: stuart_schreiber@harvard.edu
url: http://www.broad.harvard.edu/chembio/lab_schreiber/members/smdbSchreiberBio.php
day phone: 617-324-4380
Publications
1. "Chloroacetamide Photocyclization of Indole Derivatives. Synthesis, Stereochemistry, and Crystal Structure of 3,7-Methano-3-Azacycloundecino (5,4-6) Indole (Deethylquebrachamine) Derivatives" R.J. Sundberg, J.G. Luis, R.L. Parton, S. L. Schreiber, P.C. Srinivasan, P. Lamb, P. Forcier, and R.F. Bryan, J. Org. Chem, 1978, 43, 4859. download pdf
2. "Hydrogen Transfer from Tertiary Amines to Trifluoroacetic Anhydride" Stuart L. Schreiber, Tetrahedron, 1980, 21, 1027. download pdf
3. "Fragmentation Reactions of α-Alkoxy Hydroperoxides and Application to the Synthesis of the Macrolide (±)-Recifeiolide" Stuart L. Schreiber, J. Am. Chem. Soc, 1980, 102, 6163. download pdf
4. "I. Oxidation of Tertiary Amines. II. Peroxides in Organic Synthesis" Stuart L. Schreiber Ph.D. Thesis, Harvard University, 1981,
5. "A Cyclobutene Bridgehead Olefin Approach to the Germacranes" Stuart L. Schreiber and Conrad Santini, Tetrahedron, 1981, 22, 4651. download pdf
6. "Ozonolytic Cleavage of Cycloalkenes to Terminally Differentiated Products" Stuart L. Schreiber, Ronald E. Claus, and Jeff Reagan, Tetrahedron, 1982, 23, 3867. download pdf
7. "A Photochemical Route to the Formation of Threo-Aldols" Stuart L. Schreiber, Amir H. Hoveyda, and Hsien-Jen Wu, J. Am. Chem. Soc., 1983, 105, 660. download pdf
8. "Criegee Rearrangement of α-Alkoxy Hydroperoxides. A Synthesis of Esters and Lactones that Complements the Baeyer-Villiger Oxidation of Ketones" Stuart L. Schreiber and Wai-Fong Liew, Tetrahedron, 1983, 24, 2363. download pdf
9. "Total Synthesis of (±)-Talaromycin B" Stuart L. Schreiber, Toby J. Sommer, Tetrahedron, 1983, 24, 4781. download pdf
10. "Application of the Furan-Carbonyl Photocycloaddition Reaction to the Synthesis of the Bis(Tetra hydrofuran) Moiety of Asteltoxin" Stuart L. Schreiber and Kunio Satake, J. Am. Chem. Soc., 1983, 105, 6723. download pdf
11. "Ozonolytic Cleavage of Cyclohexene to Terminally Differentiated Products" Stuart L. Schreiber and Ronald E. Claus, Organic Syntheses, 1984, 64, 150.
12. "Synthesis of Oxocenones from δ-Lactones and Their Conversion to Transposed Oxocenes by a Reductive Ferrier Reaction" Stuart L. Schreiber and Sarah E. Kelly, Tetrahedron, 1984, 25, 1757. download pdf
13. "Cyclobutene Bridgehead Olefin Route to the American Cockroach Sex Pheromone, Periplanone-B" Stuart L. Schreiber and Conrad Santini, J. Am. Chem. Soc., 1984, 106, 4038. download pdf
14. "Total Synthesis of (±)-Asteltoxin" Stuart L. Schreiber and Kunio Satake, J. Am. Chem. Soc., 1984, 106, 4186. download pdf
15. "Synthetic Studies of the Furan-Carbonyl Photocycloaddition Reaction. Total Synthesis of (±)-Avenaciolide" Stuart L. Schreiber and Amir H. Hoveyda, J. Am. Chem. Soc., 1984, 106, 7200. download pdf
16. "Diastereotopic Selectivity at Prochiral Carbon Centers. A Stereodivergent Synthesis of the Talaromycins" Stuart L. Schreiber, Toby J. Sommer and Kunio Satake, Tetrahedron, 1985, 26, 17. download pdf
17. "Iron/Copper Promoted Fragmentation Reactions of α-Alkoxy Hydroperoxides. The Conversion of Octalins into 14-Membered Ring Macrolides." Stuart L. Schreiber and Wai-Fong Liew, J. Am. Chem. Soc., 1985, 107, 2980. download pdf
18. "2+2 Photocycloadditions in the Synthesis of Chiral Molecules" Stuart L. Schreiber, Science, 1985, 227, 857. download pdf
19. "Diastereotopic Selectivity at Prochiral Carbon Centers: Functionalization of Differentiated Hydroxymethyl Groups Provides Access to Either Stereoisomeric Configuration" Stuart L. Schreiber and Zhaoyin Wang, J. Am. Chem. Soc., 1985, 107, 5303. download pdf
20. "Conformational Control of Enolate Geometry: A Short Synthesis of Germacrene-D" Stuart L. Schreiber and Ronald C. Hawley, Tetrahedron, 1985, 26, 5971. download pdf
21. "Iron/Copper Promoted Fragmentation Reactions of α-Alkoxy Hydroperoxides. Regio- and Stereocontrolled Formation of Olefin Containing Macrolides" Stuart L. Schreiber, Bernard Hulin, and Wai Fong Liew, Tetrahedron, 1986, 42, 2945. download pdf
22. "Epoxidation of Unsaturated Macrolides: Stereocontrolled Routes to Ionophore Subunits" Stuart L. Schreiber, Tarek Sammakia, and Bernard Hulin, J. Am. Chem. Soc., 1986, 108, 2106. download pdf
23. "Lewis Acid Mediated Version of the Nicholas Reaction: Synthesis of Syn-Alkylated Products and Cobalt Complexed Cycloalkynes" Stuart L. Schreiber, Tarek Sammakia, and William E. Crowe, J. Am. Chem. Soc., 1986, 108, 3128. download pdf
24. "Studies of the Furan-Carbonyl Photocycloaddition Reaction: The Determination of the Absolute Stereostructure of Asteltoxin" Stuart L. Schreiber, Kunio Satake, Tetrahedron, 1986, 27, 2575. download pdf
25. "On the Preparation of Optically Active Secondary Alcohols from a 1,3-Dioxan-4-one: Substitution with Organocopper Reagents" Stuart L. Schreiber and Jeff Reagan, Tetrahedron, 1986, 27, 2945. download pdf
26. "Diastereotopic Group Selectivity at a Prostereogenic Carbon Center: Synthesis of (±)-4,8 Dimethyldecanal" Stuart L. Schreiber and Bernard Hulin, Tetrahedron, 1986, 27, 4561. download pdf
27. "Stereochemistry of the Intramolecular Enamine/Enal (Enone) Cycloaddition and Subsequent Transformations" Stuart L. Schreiber, Harold V. Meyers, and Kenneth B. Wiberg, J. Am. Chem. Soc., 1986, 108, 8274. download pdf
28. "Stuart L. Schreiber In Frontiers in the Chemical Sciences" Spindel, W.; Simon, R.M., Ed.; The American Association for the Advancement of Science, Washington D.C., 1986, 349-362.
29. "Reactions That Proceed with Enantiotopic Group and Diastereotopic Face Selectivity Can Deliver Products with Very High Enantiomeric Excess: Experimental Support of a Mathematical Model" Stuart L. Schreiber, Thomas S. Schreiber, and David B. Smith, J. Am. Chem. Soc., 1987, 109, 1525. download pdf
30. "Revised Structure of the Fungal Germination Self-inhibitor Gloeosporone" Stuart L. Schreiber, Sarah E. Kelly, Walter L. Meyer, W. Bernd Schweizer, Albert K. Beck, Werner Scheifele, and Dieter Seebach, Helv. Chim. Acta., 1987, 70, 281. download pdf
31. "Stereochemistry of the 1,2-Wittig Rearrangement: A Synthesis of Syn-1,3-Diols" Stuart L. Schreiber and Mark T. Goulet, Tetrahedron, 1987, 28, 1043. download pdf
32. "Dynamic Behavior of Dicobalt Hexacarbonyl Propargyl Cations and Their Reactions with Chiral Nucleophiles" Stuart L. Schreiber, Michael T. Klimas, Tarek Sammakia, J. Am. Chem. Soc., 1987, 109, 5749. download pdf
33. "Synthesis of a Bipolar Phosphatidylethanolamine: A Model Compound for a Membrane-Spanning Probe" Joseph M. Delfino, Charles J. Stankovic, Stuart L. Schreiber and Frederic M. Richards, Tetrahedron, 1987, 28, 2323. download pdf
34. "An Efficient Method for the Partial Synthesis of Mixed-Chain Phosphatidylethanolamines" Joseph M. Delfino, Stuart L. Schreiber and Frederic M. Richards, Tetrahedron, 1987, 2327. download pdf
35. "Chemistry Relevant to Several Compounds of Biological Interest" Stuart L. Schreiber, Program for the 30th National Organic Chemistry Symposium, Division of Organic Chemistry, American Chemistry Society, Vancouver, Canada, 1987,
36. "Two-Directional Chain Synthesis: The Enantioselective Synthesis of Syn-Skipped Polyol Chains from Meso Precursors" Stuart L. Schreiber, Mark T. Goulet and Gayle Schulte, J. Am. Chem. Soc., 1987, 109, 4718. download pdf
37. "Stereochemical Studies of the Skipped-Polyol Polyene Macrolide Class: Degradation and Partial Structure Determination of Mycoticin A and B" Stuart L. Schreiber and Mark T. Goulet, Tetrahedron, 1987, 28, 6001. download pdf
38. "Stereochemical Studies of the Skipped-Polyol Polyene Macrolide Class: NMR Studies of a Tetraformylal Derivative of Mycoticin A and B" Stuart L. Schreiber, Mark T. Goulet and Tarek Sammakia, Tetrahedron, 1987, 28, 6005. download pdf
39. "Application of the Two-Directional Chain Synthesis Strategy to the First Stereochemical Assignment of Members of the Skipped-Polyol Polyene Macrolide Class: Mycoticin A and B" Stuart L. Schreiber and Mark T. Goulet, J. Am. Chem. Soc., 1987, 109, 8120. download pdf
40. "Two-Directional Chain Synthesis and Terminus Differentiation" Stuart L. Schreiber, Chemica Scripta, 1987, 27, 563.
41. "Barriers to Rotation Adjacent to Double Bonds. 5. Remote Substituent Effects on the Syn/Skew Energy Difference for 1-Butene" Kenneth B. Wiberg and Stuart L. Schreiber, J. Org. Chem., 1988, 53, 783. download pdf
42. "Synthesis of the Bicyclic Core of the Esperamicin/Calichemicin Class of Antitumor Agents" Stuart L. Schreiber and Laura L. Kiessling, J. Am. Chem. Soc., 1988, 110, 631. download pdf
43. "Synthesis of Chemically Reactive Analogues of AZT and Their Biological Evaluation Against HIV" Stuart L. Schreiber and Norihiro Ikemoto, Tetrahedron, 1988, 29, 3211. download pdf
44. "Structural and Synthetic Studies of the Spore Germination Autoinhibitor Gloeosporone" Stuart L. Schreiber, Sarah E. Kelly, John A. Porco, Tarek Sammakia and Edward M. Suh, J. Am. Chem. Soc., 1988, 110, 6210. download pdf
45. "Synthetic Studies in the Brefeldin C Series: Asymmetric Enamine-Enal Cycloaddition and Intramolecular Nozaki Reactions" Stuart L. Schreiber and Harold V. Meyers, J. Am. Chem. Soc., 1988, 110, 5198. download pdf
46. "Group Selective Reduction of Acetals Related to the Ansa Chain of the Streptovaricins: Conformational and Stereochemical Analysis" Stuart L. Schreiber, Zhaoyin Wang and Gayle Schulte, Tetrahedron, 1988, 29, 4085. download pdf
47. "Is There a Scaffolding Domain within the Structure of the Immunosuppressive Agent Cyclosporin A (CsA)? Studies of the Cyclophilin Binding Domain of CsA" Stuart L. Schreiber, Neville J. Anthony, Bruce D. Dorsey, Ronald C. Hawley, Tetrahedron, 1988, 29, 6577. download pdf
48. "On the Use of Unsymmetrically Substituted Furans in the Furan-Carbonyl Photocycloaddition Reaction: Synthesis of a Kadsuranone-Ginkgolide Hybrid" Stuart L. Schreiber, John A. Porco, Jr., Didier Desmaele, Tetrahedron, 1988, 29, 6689. download pdf
49. "Model of the Interactions of Calichemicin γ1 with a DNA Fragment from pBR322" Stuart L. Schreiber, Ronald C. Hawley, Laura L. Kiessling, Proc. Nat. Acad. Sci. USA,, 1989, 86, 1105. download pdf
50. "Structural Fluctuations in the Head-to-Head Junction Cause Rapid Gating of the Gramicidin Channel" Stefan H. Heinemann, Frederic J. Sigworth, Charles J. Stankovic, Jose M. Delfino, Stuart L. Schreiber, Biophys. J., 1989, 55, 505a.
51. "Studies Relating to the Synthesis of the Immunosuppressive Agent FK506: Synthesis of the Cyclohexyl Moiety via a Group Selective Epoxidation" Stuart L. Schreiber and David B. Smith, J. Org. Chem., 1989, 54, 9. download pdf
52. "Studies Relating to the Synthesis of the Immunosuppressive Agent FK506: Application of the Two Directional Chain Synthesis Strategy to the Pyranose Moiety" Stuart L. Schreiber, Tarek Sammakia, David E. Uehling, J. Org. Chem., 1989, 54, 15. download pdf
53. "Studies Relating to the Synthesis of the Immunosuppressive Agent FK506: Coupling of Fragments via a Stereoselective Trisubstituted Olefin Forming Reaction Sequence" Stuart L. Schreiber, Samuel J. Danishefsky, John A. Ragan, David B. Smith, Brian Jones, Masahiko Yamaguchi, J. Org. Chem., 1989, 54, 17. download pdf
54. "Transmembrane Channels Based on Tartaric Acid-Gramicidin Hybrids" Charles J. Stankovic, Stefan H. Heinemann, Jose M. Delfino, Frederick J. Sigworth, Stuart L. Schreiber, Science, 1989, 244, 813. download pdf
55. "Studies of the Furan-Carbonyl Photocycloaddition Reaction: Vinylic Substitution Reactions" Stuart L. Schreiber and John A. Porco, Jr., J. Org. Chem., 1989, 54, 4721. download pdf
56. "Further Investigations of the Type II Diels-Alder Route to the Bicyclic Core of Esperamicin/ Calichemicin Reveal a Regiochemical Misassignment: Meta vs. Para Selectivity" Stuart L. Schreiber and Laura L. Kiessling, Tetrahedron Lett, 1989, 30, 433. download pdf
57. "Intramolecular SN Cleavage of Allylic Ethers by Enolate Anions" Leo A. Paquette, Jeff Reagan, Stuart L. Schreiber, Christopher A. Teleha, J. Am. Chem. Soc., 1989, 111, 2331. download pdf
58. "Studies of the Immunosuppressive Agent FK506: Synthesis of an Advanced Intermediate" John A. Ragan, Masashi Nakatsuka, David B. Smith, Stuart L. Schreiber, J. Org. Chem., 1989, 54, 4267. download pdf
59. "A Receptor for the Immunosuppressant FK506 is a cis-trans Peptidyl-Prolyl Isomerase" Matthew W. Harding, Andrzej Galat, David E. Uehling, and Stuart L. Schreiber, Nature, 1989, 341, 758. download pdf
60. "Synthesis and Crystallographic Analysis of a Bicyclic Core Related to the Esperamicin/Calichemicin Aglycones" Greg VanDuyne, Jon Clardy, Frank J. Schoenen, John A. Porco, Jr., and Stuart L. Schreiber, Tetrahedron Lett., 1989, 30, 3765. download pdf
61. "Stereochemical Studies of Simple Cyclooctyl Systems" David B. Smith and Stuart L. Schreiber, J. Org. Chem., 1989, 54, 5994. download pdf
62. "Gating Phenomena in Covalently Linked Gramicidin Channels" Stefan H. Heinemann, Charles J. Stankovic, Stuart L. Schreiber, Biophys. J., 1989, 55, 55.
63. "The Development of a PAF Receptor Binding Model: A Progress Report" Stuart L. Schreiber, Ronald C. Hawley, John A. Porco, Jr., Didier Desmaele, New Methods in Drug Research, A. Makriyannis, Ed., Vol 3, J. R. Prous, Barcelona, 1989, 3,
64. "Purification of Gramicidin A" Charles J. Stankovic, Jose M. Delfino and Stuart L. Schreiber, Analytical Biochemistry, 1990, 184, 100. download pdf
65. "Structure and Basicity of Silyl Ethers: A Crystallographic and Ab Initio Inquiry into the Nature of Silicon-Oxygen Interactions" James F. Blake, Scott G. Wierschke, William L. Jorgensen, Soroosh Shambayati, Stuart L. Schreiber, J. Am. Chem. Soc., 1990, 112, 697. download pdf
66. "Overproduction and Dissection of Proteins by the Expression Cassette Polymerase Chain Reaction" Kurtis MacFerrin, Stuart L. Schreiber, and Gregory Verdine, Proc. Natl. Acad. Sci. USA, 1990, 87, 1937. download pdf
67. "Die Bedeutung elektronischer Effekte fur die Konformation" Soroosh Shambayati, William E. Crowe, and Stuart L. Schreiber, Angew. Chemie., 1990, 102, 290.
68. "On the Conformation and Structure of Organometal Complexes in the Solid State: Two Studies Relevant to Chemical Synthesis" Soroosh Shambayati, William E. Crowe, and Stuart L. Schreiber, Angew. Chemie, Int. Ed. Eng., 1990, 29, 256. download pdf
69. "Stereochemical Studies of Epoxides Relevant to the Ansa Chain of the Streptovaricins" Zhaoyin Wang and Stuart L. Schreiber, Tetrahedron Lett., 1990, 31, 31. download pdf
70. "Mechanisms of Immunosuppression by FK506: Preservation of T Cell Transmembrane Signal Transduction" Barbara E. Bierer, Stuart L. Schreiber, and Steven J. Burakoff, Transplantation, 1990, 49, 1168.
71. "Cloning, Expression, and Purification of Human Cyclophilin in E. coli and Assessment of the Catalytic Role of Cysteines by Site-Directed Mutagenesis" Jun Liu, Mark W. Albers, Chih-ming Chen, Stuart L. Schreiber, Christopher T. Walsh, Proc. Natl. Acad Sci., U. S. A., 1990, 87, 2304. download pdf
72. "An Asymmetric Synthesis of Cryptone" Ronald C. Hawley and Stuart L. Schreiber, Synth. Commun., 1990, 20, 1159.
73. "Immobilizing the Gate of a Tartaric Acid-Gramacidin Hybrid Channel Molecule by Rational Design" Charles J. Stankovic, Stefan H. Heinemann, Stuart L. Schreiber, J. Am. Chem. Soc., 1990, 112, 3702. download pdf
74. "Total Syntheses of FK506 and an FKBP Probe Reagent, (C8, C9-13C2)-FK506" Masashi Nakatsuka, John A. Ragan, Tarek Sammakia, David B. Smith, David E. Uehling, and Stuart L. Schreiber, J. Am. Chem. Soc., 1990, 112, 5583. download pdf
75. "The Asymmetric Epoxidation of Divinyl Carbinols" David B. Smith, Zhaoyin Wang, and Stuart L. Schreiber, Tetrahedron, 1990, 46, 4793. download pdf
76. "Inhibition of FKBP Rotamase Activity by Immunosuppressant FK506: A Twisted Amide Surrogate" Michael K. Rosen, Robert F. Standaert, Andrzej Galat, Masashi Nakatsuka, and Stuart L. Schreiber, Science, 1990, 248, 863. download pdf
77. "Prevention of HIV-1 Infection and Preservation of CD4 Function by the Binding of CPFs to gp120" Robert W. Finberg, David C. Diamond, Darren B. Mitchell, Yvonne Rosenstein, Gopalan Soman, Thea C. Norman, Stuart L. Schreiber, Steven J. Burakoff, Science, 1990, 249, 287. download pdf
78. "Site Specific Atom Transfer From DNA to a Bound Ligand Defines the Geometry of a DNA Calicheamicin g1 Complex" James DeVoss, Craig Townsend, Nada Zein, Wei-Dung Ding, George O. Morton, George A. Ellestad, Alethea B. Tabor, Stuart L. Schreiber, J. Am. Chem. Soc., 1990, 112, 9669. download pdf
79. "Molecular Cloning and Overexpression of the Human FK506-Binding Protein, FKBP" Robert F. Standaert, Andrzej Galat, Gregory L. Verdine, and Stuart L. Schreiber, Nature, 1990, 346, 671. download pdf
80. "Identification and Structural Analysis of Residues in the V1 Region of CD4 Involved in Interactions with Human Immuno deficiency Virus gp120 and class II major histocompatibility complex molecules" Michael Bowman, Kurtis D. MacFerrin, Stuart L. Schreiber, and Steven J. Burakoff, Proc. Natl. Acad. Sci, U. S. A., 1990, 87, 9052. download pdf
81. "Two Distinct Signal Transmission Pathways in T Lymphocytes are Inhibited by Complexes Formed Between an Immunophilin and Either FK506 or Rapamycin" Barbara E. Bierer, Petri S. Mattila, Robert F. Standaert, Leonard A. Herzenberg, Steven J. Burakoff, Gerald Crabtree, Stuart L. Schreiber, Proc. Natl. Acad. Sci, U. S. A., 1990, 87, 9231. download pdf
82. "Substrate Specificity for the Human Rotamase FKBP: A View of FK506 and Rapamycin as Leucine (twisted amide)-Proline Mimics" Mark W. Albers, Christopher T. Walsh, Stuart L. Schreiber, J. Org. Chem., 1990, 55, 4984. download pdf
83. "A Transannular Diels-Alder Route to Systems Related to Dynemicin A" John A. Porco, Jr., Frank J. Schoenen, Thomas J. Stout, Jon Clardy, Stuart L. Schreiber, J. Am. Chem. Soc., 1990, 112, 7410. download pdf
84. "Probing Immunosuppressant Action with a Nonnatural Immunophilin Ligand" Barbara E. Bierer, Patricia K. Somers, Thomas J. Wandless, Steven J. Burakoff, Stuart L. Schreiber, Science, 1990, 250, 556. download pdf
85. "N-Oxide Promoted Pauson-Khand Cyclizations at Room Temperature" Soroosh Shambayati, William E. Crowe, Stuart L. Schreiber, Tetrahedron, 1990, 31, 5289. download pdf
86. "Total Synthesis of FK506 and an FKBP Probe Reagent, (C8,C9-13C)-FK506: An Investigation of the FK506/FKBP Complex" Masashi Nakatsuka and Stuart L. Schreiber, Tennen Yuki Toronkai Koen Yoshishu, 1990, 32, 694-701. download pdf
87. "Total Synthesis of the Anthelmintic Agent Hikizimycin" Norihiro Ikemoto and Stuart L. Schreiber, J. Am. Chem. Soc., 1990, 112, 9657. download pdf
88. "Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands" Stuart L. Schreiber, Science, 1991, 251, 283-287. download pdf
89. "p-Bond Hybridization in Transition Metal Complexes: A Stereoelectronic Model for Conformational Analysis" William E. Crowe and Stuart L. Schreiber, Advances in Metal-Organic Chemistry, Ed. L. Liebeskind, JAI Press, 1991, 2, 247-267.
90. "Rapamycin and FK506 Binding Proteins (Immunophilins)" Heinz Fretz, Mark W. Albers, Andrzej Galat, Robert F. Standeart, William S. Lane, Steven J. Burakoff, Barbara E. Bierer, Stuart L. Schreiber, J. Am. Chem. Soc., 1991, 113, 1409-1411. download pdf
91. "Synthesis of the Angular Anthraquinone Subunit of Dynemicin A" Hidenori Chikashita, John A. Porco, Jr., Stuart L. Schreiber, J. Org. Chem., 1991, 56, 1692. download pdf
92. "The Effect of the Immunosuppressant FK506 on Alternate Pathways of T Cell Activation" Barbara E. Bierer, Stuart L. Schreiber, Steven J. Burakoff, Eur. J. Immunol., 1991, 21, 439-445.
93. "FK506 and Rapamycin Binding to FKBP: Common Elements Involved in Immunophilin-Ligand Complexation" Thomas J. Wandless, Stephen W. Michnick, Michael K. Rosen, Martin Karplus, Stuart L. Schreiber, J. Am. Chem. Soc., 1991, 113, 2339-2341. download pdf
94. "Complete Amino Acid Sequence of the FK506 and Rapamycin Binding Protein, FKBP, Isolated from Calf Thymus" Andrzej Galat, William Lane, Matthew W. Harding, Stuart L. Schreiber, J. Prot. Chem., 1991, 10, 151-160.
95. "Inhibition of IgE Receptor-Mediated Exocytosis from Rat Basophilic Leukemia Cells by FK506 is Reversed by Rapamycin: Evidence for Common Signaling Pathways in Mast Cells and T Lymphocytes" Thomas Hultsch, Stuart L. Schreiber, Robert H. Hohman, FASEB J., 1991, 5, A1008 (3705).
96. "Protein Overproduction for Organic Chemists" Stuart L. Schreiber and Gregory L. Verdine, Tetrahedron, 1991, 47, 2543-2562. download pdf
97. "Molecular Design of Transmembrane Ion Channels" Charles J. Stankovic and Stuart L. Schreiber, ChemTracts, Organic Chemistry,, 1991, 4, 1-20.
98. "The Interaction of CD4 with HIV-1 GP120" S. L. Silberman, S. J. Goldman, D. B. Mitchell, A. Tong, Y. Rosenstein, D. Diamond, R. Finberg, S. L. Schreiber, S. J. Burakoff, Semin. Immunol., 1991, 3, 187-192.
99. "Proton and Nitrogen Sequential Assignments and Secondary Structure Determination of the Human FK506 and Rapamycin Binding Protein" Michael K. Rosen, Stephen W. Michnick, Martin Karplus, Stuart L. Schreiber, Biochemistry, 1991, 30, 4774-4789. download pdf
100. "Photomodulated Ion Channels Based on Covalently Linked Gramicidins" Charles J. Stankovic, Stefan H. Heinemann, Stuart L. Schreiber, Biochem. et Biophys. Acta, 1991, 1061, 163-170.
101. "Solution Structure of FKBP, a Rotamase Enzyme and Receptor for FK506 and Rapamycin" Stephen W. Michnick, Michael K. Rosen, Thomas J. Wandless, Martin Karplus, Stuart L. Schreiber, Science, 1991, 252, 836-839. download pdf
102. "Atomic Structure of FKBP-FK506, an Immunophilin-Immunosuppressant Complex" Gregory D. Van Duyne, Robert F. Standaert, P. Andrew Karplus, Stuart L. Schreiber, Jon Clardy, Science, 1991, 252, 839-842. download pdf
103. "FKBP, Thought to Be Identical to PKCI-2, Does Not Inhibit Protein Kinase C" Mark W. Albers, Jun Liu, Sandra E. Wilkinson, Julie Wadsworth, Dolores Perez-Sal, Robert R. Rando, John S. Nixon, Stuart L. Schreiber, BioMed., 1991, 1, 205-210.
104. "The Relationship of FKBP to PKCI-2" Mark W. Albers, Jun Liu, Stuart L. Schreiber, Nature, 1991, 351, 527. download pdf
105. "Immunophilin Ligands Demonstrate Common Features of Signal Transduction Leading to Exocytosis or Transcription" Thomas Hultsch, Mark W. Albers, Stuart L. Schreiber, Robert J. Hohman, Proc. Natl. Acad. Sci, U. S. A., 1991, 88, 6229-6233. download pdf
106. "Molecular Cloning of a Membrane-Associated Human FK506 and Rapamycin Binding Protein, FKBP-13" Yong-Jiu Jin, Mark W. Albers, William S. Lane, Barbara E. Bierer, Stuart L. Schreiber, Steven J. Burakoff, Proc. Natl. Acad. Sci., U. S. A., 1991, 88, 6677-6681. download pdf
107. "Calcineurin is a Common Target of Cyclophilin-Cyclosporin A and FKBP-FK506 Complexes" Jun Liu, Jesse D. Farmer, William S. Lane, Jeff Friedman, Irving Weissman, Stuart L. Schreiber, Cell, 1991, 66, 807-815. download pdf
108. "The Atomic Structure of the Rapamycin-Human Immunophilin FKBP12 Complex" Gregory D. Van Duyne, Robert F. Standaert, Stuart L. Schreiber, Jon Clardy, J. Am. Chem. Soc., 1991, 113, 7433-7434. download pdf
109. "Immunophilin-Ligand Complexes as Probes of Intracellular Signaling Pathways" Stuart L. Schreiber, Jun Liu, Mark W. Albers, Eugene Koh, Rakesh Karmacharya, Patrick K. Martin, Michael K. Rosen, Robert F. Standaert, Thomas J. Wandless, Transplantation Proceedings, 1991, 23, 2851-2857. download pdf
110. "Synthesis and Analysis of 506BD, a High Affinity Ligand to the Immunophilin, FKBP" Patricia K. Somers, Thomas J. Wandless, Stuart L. Schreiber, J. Am. Chem. Soc., 1991, 113, 8045-8056. download pdf
111. "Thermodynamic Spiroketalization as an Efficient Method for Remote Asymmetric Induction" Nancy I. Totah and Stuart L. Schreiber, J. Org. Chem., 1991, 56, 6255. download pdf
112. "The Study of Receptor-Ligand Interactions Through Receptor Labeling and Isotope-Edited NMR" Michael K. Rosen, Thomas J. Wandless, Stuart L. Schreiber, J. Org. Chem., 1991, 56, 6262. download pdf
113. "Hepatotrophic Properties in Dogs of Human FKBP, the Binding Protein for FK506 and Rapamycin" Thomas E. Starzl, Stuart L. Schreiber, Mark W. Albers, Kendrick A. Porter, Carlo Scotti Foglieni, Antonio Francavilla, Transplantation, 1991, 52, 751-753.
114. "The Paterno-Buchi Reaction" John A. Porco, Jr. and Stuart L. Schreiber, Comprehensive Organic Synthesis, Paquette, L. A.. Ed.; Pergamon Press: Oxford,, 1991, 5, 151-192.
115. "Lewis Acid-Carbonyl Complexation" Soroosh Shambayati and Stuart L. Schreiber, Comprehensive Organic Synthesis; Schreiber, S. L. Ed.; Pergamon Press: Oxford, 1991, 1, 283-324.
116. "Total Synthesis of the Complex of the FK506/FKBP Complex" Stuart L. Schreiber, John A. Ragan, Robert F. Standaert, Strategies and Tactics in Organic Synthesis, Lindberg, T. Ed.; Academic Press: San Diego, 1991, 3, 417-461.
117. "Total Syntheses of FK506 and an FKBP Probe Reagent (C8, C9-13C2)-FK506: Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands" Masashi Nakatsuka and Stuart L. Schreiber, Yuki Gosei Kagaku Kyokaishi, 1991, 49, 748-761. download pdf
118. "A Rapamycin-Selective 25 kDa Immunophilin" A. Galat, William S. Lane, Robert F. Standaert, Stuart L. Schreiber, Biochemistry, 1992, 31, 2427-2434. download pdf
119. "The Mechanism of Action of Cyclosporin A and FK506" Stuart L. Schreiber and Gerald R. Crabtree, Immunology Today, 1992, 13, 136-142.
120. "Total Synthesis of (-)-Hikizimycin Using the Strategy of Two-Directional Chain Synthesis" Norihiro Ikemoto and Stuart L. Schreiber, J. Am. Chem. Soc., 1992, 114, 2524-2536. download pdf
121. "Molecular Recognition of Immunophilins and Immunophilin-Ligand Complexes" Stuart L. Schreiber, Jun Liu, Mark W. Albers, Michael K. Rosen, Robert F. Standaert, Thomas J. Wandless, Patricia K. Somers, Tetrahedron, 1992, 13, 2545-2558. download pdf
122. "Naturstoffe als Sonden zum Studium zellularer Funktionen ­p; Untersuchungen von Immunophilinen" Michael K. Rosen and Stuart L. Schreiber, Angew. Chemie., 1992, 104, 413-430. download pdf
123. "Inhibition of T Cell Signaling by Immunophilin-Ligand Complexes Correlates With Loss of Calcineurin Phosphatase Activity" Jun Liu, Mark W. Albers, Thomas J. Wandless, S. Luan, David G. Alberg, Peter J. Belshaw, Philip Cohen, Carol MacIntosh, Claude B. Klee, Stuart L. Schreiber, Biochemistry, 1992, 31, 3896-3901. download pdf
124. "Rapamycin Inhibits Liver, Kidney, and Intestine Regeneration" A. Francavilla, T. E. Starzl, C. Scotti, C. Carrieri, S. Azzarone, D. H. Zeng, K. A. Porter, S. L. Schreiber, Transplantation, 1992, 53, 496-498.
125. "cDNA Cloning of a 25 kDa FK506 and Rapamycin Binding Protein" Deborah T. Hung and Stuart L. Schreiber, Biochem. Biophys. Res. Commun., 1992, 184, 733-738.
126. "Association of a 59-Kilodalton Immunophilin with the Glucocorticoid Receptor Complex" Ping-K. K. Tai, Mark W. Albers, Hong Chang, Lee E. Faber, Stuart L. Schreiber, Science, 1992, 256, 1315-1318. download pdf
127. "CPF-DD is an Inhibitor of Infection by Human Immunodeficiency Viruses and Other Enveloped Viruses in Vitro" John P. Moore, Guy Simpson, Jane E. McKeating, Steven J. Burakoff, Stuart L. Schreiber, Robin A. Weiss, Virology, 1992, 188, 537-544.
128. "Natural Products as Probes of Cellular Function: Studies of Immunophilins" Michael K. Rosen and Stuart L. Schreiber, Angew. Chemie, Int. Ed. Eng., 1992, 31, 384-400. download pdf
129. "Application of the Allylic Diazene Rearrangement: Synthesis of the Enediyne-Bridged Tricyclic Core of Dynemicin A" John L. Wood, John A. Porco, Jr., Jack W. Taunton, Angela J. Lee, Jon Clardy, Stuart L. Schreiber, J. Am. Chem. Soc., 1992, 114, 5900-5902. download pdf
130. "The Conformation of Cyclosporin A Bound to Cyclophilin is Altered (Once Again) Following Binding to Calcineurin: An Analysis of Receptor-Ligand-Receptor Interactions" Michael K. Rosen, Peter J. Belshaw, David G. Alberg, Stuart L. Schreiber, BioMed., 1992, 2, 747-753. download pdf
131. "Vinylogous Polypeptides: An Alternative Peptide Backbone" Masahiko Hagihara, Neville J. Anthony, Thomas J. Stout, Jon Clardy, Stuart L. Schreiber, J. Am. Chem. Soc., 1992, 114, 6568-6570. download pdf
132. "Reassignment of Stereochemistry and Total Synthesis of the Thrombin Inhibitor Cyclotheonamide B" Masahiko Hagihara and Stuart L. Schreiber, J. Am. Chem. Soc., 1992, 114, 6570-6571. download pdf
133. "Immunophilin-Sensitive Phosphatase Action in Cell Signaling Pathways" Stuart L. Schreiber, , Cell, 1992, 70, 365-368. download pdf
134. "Molecular Recognition of Immunophilins and Immunophilin-Ligand Complexes" Stuart L. Schreiber, Jun Liu, Mark W. Albers, Michael K. Rosen, Robert F. Standaert, Thomas J. Wandless, Patricia K. Somers, Proceedings of The Robert A.Welch Foundation Conference on Chemical Research XXXV: Chemistry at the Frontiers of Medicine Ch 4, 87-102,, 1992,
135. "Effects of Cyclosporin A and FK506 on Fce Receptor type I-Initiated Increases in Cytokine mRNA in Mouse Bone Marrow-Derived Progenito Mast Cells: Resistance to FK506 is Associated with a Deficiency in FKBP12" Randall E. Kaye, David A. Fruman, Barbara E. Bierer, Mark W. Albers, Lynne D. Zydowsky, Susanna I. Ho, Yong-Jiu Jin, Maria C. Castells, Stuart L. Schreiber, Christopher T. Walsh, K. Frank Austen, Howard R. Katz, Proc. Natl. Acad. Sci., USA, 1992, 89, 8542-8546. download pdf
136. "Synthetic Investigations of Rapamycin. 1. Synthesis of a C10-C21 Fragment" Stephanie D. Meyer, Tetsuo Miwa, Masashi Nakatsuka, Stuart L. Schreiber, J. Org. Chem., 1992, 57, 5058-5060. download pdf
137. "Synthetic Investigations of Rapamycin. 2. Synthesis of a C22-C42 Fragment" Daniel Romo, Donna D. Johnson, Louis Plamondon, Tetsuo Miwa, Stuart L. Schreiber, J. Org. Chem., 1992, 57, 5060-5063. download pdf
138. "Using the Principles of Organic Chemistry to Explore Cell Biology" Stuart L. Schreiber, C.& E. News, 1992, Oct. 26, 22-32.
139. "Solution Conformation of the SH3 Domain of Src and Identification of Its Ligand-Binding Site" Hongtao Yu, Michael K. Rosen, Tae Bum Shin, Cynthia Seidel-Dugan, Joan S. Brugge, Stuart L. Schreiber, Science, 1992, 258, 1665. download pdf
140. "Chromosomal Band Assignments of the Genes Encoding Human FKBP12 and FKBP13" Anthony G. DiLella, Anita Hawkins, Robert J. Craig, Stuart L. Schreiber, Constance Griffin, Biochem. Biophys. Res. Commun., 1992, 189, 819-823.
141. "Protein Overproduction Using the Expression-Cassette Polymerase Chain Reaction" K. D. MacFerrin, L. Chen, M. P. Terranova, S. L. Schreiber, G. L Verdine, Meth. Enzymol., 1993, 217, 79-102.
142. "A Composite FKBP12-FK506 Surface That Contacts Calcineurin" Dan Yang, Michael K. Rosen, Stuart L. Schreiber, J. Am. Chem. Soc., 1993, 115, 819-820. download pdf
143. "Activation of an Inactive Immunophilin by Mutagenesis" Michael K. Rosen, Dan Yang, Patrick K. Martin, Stuart L. Schreiber, J. Am. Chem. Soc., 1993, 115, 821-822. download pdf
144. "Atomic Structures of the Human Immunophilin FKBP12 Complexes with FK506- and Rapamycin" Gregory D. Van Duyne, Robert F. Standaert, P. Andrew Karplus, Stuart L. Schreiber, Jon Clardy, J. Mol. Biol., 1993, 229, 105-124. download pdf
145. "Structure of PI3K SH3 Domain and Analysis of the SH3 Family" Satoshi Koyama, Hongtao Yu, David C. Dalgarno, Tae Bum Shin, Lynne D. Zydowsky, Stuart L. Schreiber, Cell, 1993, 72, 945-952. download pdf
146. "Immunosuppressants Implicate Protein Phosphatase Regulation of K+ Channels in Guard Cells" Sheng Luan, Weiwei Li, Frank Rusnak, Sarah L. Assmann, Stuart L. Schreiber, Proc. Natl. Acad. Sci., USA, 1993, 90, 2202-2206. download pdf
147. "Two-Directional Chain Synthesis: An Application to the Synthesis of (+)-Mycoticin A" Christopher S. Poss, Scott D. Rychnovsky, Stuart L. Schreiber, J. Am. Chem. Soc., 1993, 115, 3360-3361. download pdf
148. "Design, Synthesis, and Properties of a Photoactivatable Membrane-Spanning Phospholipidic Probe" Jose M. Delfino, Stuart L. Schreiber, Frederic M. Richards, J. Am. Chem. Soc., 1993, 115, 3458-3474. download pdf
149. "1H and 15N Assignments and Secondary Structure of Src SH3 Domain" Hongtao Yu, Michael K. Rosen, Stuart L. Schreiber, FEBS Lett., 1993, 324, 87-92. download pdf
150. "1H and 15N Assignments and Secondary Structure of PI3K SH3 Domain" Satoshi Koyama, Hongtao Yu, David C. Dalgarno, Tae Bum Shin, Lynne D. Zydowski, Stuart L. Schreiber, FEBS Lett., 1993, 324, 93-98. download pdf
151. "Convenient Methods for Patterning the Adhesion of Mammalian Cells to Surfaces Using Self Assembled Monolayers of Alkanethiolates on Gold" Gabriel P. Lopez, Mark. W. Albers, Stuart L. Schreiber, Reed Carroll, Ernest Peralta, and George M. Whitesides, J. Am. Chem. Soc., 1993, 115, 5877 5878. download pdf
152. "Identification of the Immunophilins Capable of Mediating Inhibition of Signal Transduction by Cyclosporin A and FK506: Roles of Calcineurin Binding and Cellular Location" Richard J. Bram, Deborah T. Hung, Patrick K. Martin, Stuart L. Schreiber, Gerald Crabtree, Molec. Cell Biol., 1993, 13, 4760-4769. download pdf
153. "The Cell Cycle, Signal Transduction, and Immunophilin-Ligand Complexes" Stuart L. Schreiber, Mark W. Albers, Eric J. Brown, Acc. Chem. Res., 1993, 26, 412-420. download pdf
154. "Total Synthesis of Rapamycin Using an Evans-Tischenko Fragment Coupling" Daniel Romo, Stephanie D. Meyer, Donna D. Johnson, Stuart L. Schreiber, J. Am. Chem. Soc., 1993, 115, 7906-7907. download pdf
155. "P59 (FK506 Binding Protein 59) Interaction with Heat Shock Proteins is Highly Conserved and May Involve Proteins Other Than Steroid Receptors" Ping-kaung K. Tai, Hong Chang, Mark W. Albers, Stuart L. Schreiber, David O. Toft, Lee A. Faber, Biochemistry, 1993, 32, 8842-8847. download pdf
156. "FKBP-Rapamycin Blocks the Activation of Cyclin D-Cdk Complexes and the Expression of Subsequent Cyclins in MG-63 Cells" Mark W. Albers, Richard T. Williams, Eric J. Brown, Frederick L. Hall, Stuart L. Schreiber, J. Biol. Chem., 1993, 268, 22825-22829. download pdf
157. "Cyclosporin- and FK506-Induced Sympathetic Activation Correlates With Calcineurin-Mediated Inhibition of T-Cell Signaling" Teresa Lyson, LeAnn D. Ermel, Peter J. Belshaw, David G. Alberg, Stuart L. Schreiber, Ronald G. Victor, Circulation Res., 1993, 73, 596-602. download pdf
158. "Structure-Based Design of a Cyclophilin-Calcineurin Bridging Ligand" David G. Alberg and Stuart L. Schreiber, Science, 1993, 262, 248-250. download pdf
159. "Total Syntheses of Di- and Tri-O-Methyl Dynemicin A Methyl Esters" Jack Taunton, John L. Wood, Stuart L. Schreiber, J. Am. Chem. Soc., 1993, 115, 10378-10379. download pdf
160. "Structure-Based Design of an Acyclic Ligand That Bridges FKBP12 and Calcineurin" Merritt B. Andrus and Stuart L. Schreiber, J. Am. Chem. Soc., 1993, 115, 10420-10421. download pdf
161. "Controlling Signal Transduction with Synthetic Ligands" David Spencer, Thomas J. Wandless, Stuart L. Schreiber, Gerald R. Crabtree, Science, 1993, 262, 1019-1024. download pdf
162. "An FKBP-Rapamycin Sensitive, Cyclin-Dependent Kinase Activity That Correlates With the FKBP Rapamycin-Induced G1 Arrest Point in MG-63 Cells" Mark W. Albers, Eric J. Brown, Richard Williams, Frederic Hall, Stuart L. Schreiber, Annals of N. Y. Acad. Sci., 1993, 696, 54-62.
163. "Sequential Assignment and Structure Determination of Spider Toxin w-Aga-IVB" Hongtao Yu, Michael K. Rosen, Nicholas A. Saccomano, Douglas Phillips, Robert A. Volkmann, Stuart L. Schreiber, Biochemistry, 1993, 32, 13123-13129. download pdf
164. "FKBP54, a Novel FK506 Binding Protein in Avian Progesterone Receptor Complexes and HeLa Extracts" David F. Smith, Mark W. Albers, Stuart L. Schreiber, Karen L. Leach, Martin R. Deibel, Jr., J. Biol. Chem., 1993, 268, 24270-24273. download pdf
165. "Biased Combinatorial Libraries: Novel Ligands for the SH3 Domain of Phosphatidylinositol 3 Kinase" James K. Chen, William S. Lane, Andrew Brauer, Akito Tanaka, Stuart L. Schreiber, J. Am. Chem. Soc., 1993, 115, 12591-12592. download pdf
166. "Atomic Structure of the Trypsin-Cyclotheonamide A Complex: Lessons for the Design of Serine Protease Inhibitors" Angela Y. Lee, Masahiko Hagihara, Rakesh Karmacharya, Mark W. Albers, Stuart L. Schreiber, Jon Clardy, J. Am. Chem. Soc., 1993, 115, 12619-12620. download pdf
167. "Total Synthesis of the Immunosuppressive Agent (-)-Discodermolide" Jennie B. Nerenberg, Deborah T. Hung, Patricia K. Somers, Stuart L. Schreiber, J. Am. Chem. Soc., 1993, 115, 12621-12622. download pdf
168. "Crystal Structures of Cyclophilin A Complexed with Cyclosporin A and N-methyl-4-(E)-2-Butenyl-4,4-Dimethylthreonine Cyclosporin A" Hengming Ke, Peter J. Belshaw, David G. Alberg, Stuart L. Schreiber, Zhi Yuh Chang, Felicia A. Etzkorn, Susanna Ho, Christopher T. Walsh, Structure, 1994, 2, 33-44. download pdf
169. "Neocarzinostatin Activation: Molecular Modeling Revisited" Daniel Elbaum, Stuart L. Schreiber, BioMed. Chem. Lett., 1994, 4, 309-314. download pdf
170. "Two-Directional Chain Synthesis and Terminus Differentiation" Christopher S. Poss and Stuart L. Schreiber, Acc. Chem. Res., 1994, 27, 9-17. download pdf
171. "Light-Regulated, Tissue-Specific Expression of Immunophilins in a Higher Plant" Sheng Luan, Mark W. Albers, Stuart L. Schreiber, Proc. Natl. Acad. Sci. USA, 1994, 91, 984-988. download pdf
172. "Synthesis and Investigations of Enetetraynes" Daniel Elbaum, Toan B. Nguyan, William L. Jorgensen, Stuart L. Schreiber, Tetrahedron, 1994, 50, 1503-1518. download pdf
173. "Structural Basis for the Binding of Proline-Rich Peptides to SH3 Domains" Hongtau Yu, James K. Chen, Sibo Feng, David C. Dalgarno, Andrew W. Brauer, Stuart L. Schreiber, Cell, 1994, 76, 933-945. download pdf
174. "Regulated Intracellular Association of Proteins Using Cell-Permeable Synthetic Ligands" Stuart L. Schreiber and Gerald R. Crabtree, Chem. & Biol., 1994, xx-xxi.
175. "A b-Lactone Related to Lactacystin Induces Neurite Outgrowth in a Neuroblastoma Cell Line and Inhibits Cell Cycle Progression in an Osteosarcoma Cell Line" Gabriel Fenteany, Robert F. Standaert, Gregory A. Reichard, E. J. Corey, Stuart L. Schreiber, Proc. Natl. Acad. Sci., USA, 1994, 91, 3358-3362. download pdf
176. "Atomic Structure of the Immunophilin FKBP13-FK506 Complex: Insights Into the Composite Binding Surface for Calcineurin" L. Wayne Schultz, Patrick K. Martin, Jun Liang, Stuart L. Schreiber, Jon Clardy, J. Am. Chem. Soc., 1994, 116, 3129-3130. download pdf
177. "Structural Basis for Peptidomimicry by a Natural Product" Yoshihara Ikeda, Wayne Schultz, Jon Clardy, Stuart L. Schreiber, J. Am. Chem. Soc., 1994, 116, 4143-4144. download pdf
178. "Affinity Capillary Electrophoresis: Insights Into the Binding of SH3 Domains by Peptides Derived from an SH3-Binding Protein" Frank A. Gomez, James K. Chen, Akito Tanaka, Stuart L. Schreiber, George M. Whitesides, J. Org. Chem., 1994, 59, 2885-2886. download pdf
179. "Synthesis, Structure and Mechanism in Immunophilin Research" Peter J. Belshaw, Stephanie D. Meyer, Donna D. Johnson, Daniel Romo, Yoshihara Ikeda, Merritt Andrus, David G. Alberg, L. Wayne Schultz, Jon Clardy, Stuart L. Schreiber, SynLett, 1994, 381-392. download pdf
180. "GTP-Dependent Binding of the Antiproliferative Agent Didemnin to Elongation Factor 1a" Craig M. Crews, Jon L. Collins, William S. Lane, Marc L. Snapper, Stuart L. Schreiber, J. Biol. Chem., 1994, 269, 15411-15414. download pdf
181. "A Mammalian Protein Targeted by G1-Arresting Rapamycin-Receptor Complex" Eric J. Brown, Mark W. Albers, Tae Bum Shin, Kazuo Ichikawa, Curtis T. Keith, William S. Lane, Stuart L. Schreiber, Nature, 1994, 369, 756-758. download pdf
182. "Cobalt-Mediated Total Synthesis of (+)-Epoxydictymene" Timothy F. Jamison, Soroosh Shambayati, William E. Crowe, Stuart L. Schreiber, J. Am. Chem. Soc., 1994, 116, 5505-5506. download pdf
183. "SH3 Domain-Mediated Dimerization of an N-Terminal Fragment of the Phosphatidylinositol 3-Kinase p85 Subunit" James K. Chen and Stuart L. Schreiber, BioMed. Chem. Lett., 1994, 4, 1755-1760. download pdf
184. "pCyp B: A Chloroplast-Localized, Heat Shock-Responsive Cyclophilin from Fava Bean" Sheng Luan, William S. Lane, and Stuart L. Schreiber, Plant Cell, 1994, 6, 885-892. download pdf
185. "Signalling an Interest" Hongtao Yu and Stuart L. Schreiber, Nature Struct. Biol., 1994, 1, 417-420. download pdf
186. "Calcineurin Mediates Human Tumor Necrosis Factor-alpha Gene Induction in Stimulated T and B Cells" Anne E. Goldfeld, Eunice Tsai, Randall Kincaid, Peter J. Belshaw, Stuart L. Schreiber, Jack L. Strominger, Anjana Rao, J. Exp. Med., 1994, 180, 763-768. download pdf
187. "Distinct Binding and Cellular Properties of Synthetic (+)- and (-)-Discodermolide" Deborah T. Hung, Jennie B. Nerenberg, Stuart L. Schreiber, Chem. & Biol., 1994, 1, 67-71. download pdf
188. "Potentiation of Progesterone Receptor-Mediated Transcription by the Immunosuppressant FK506" Ping-Kaung Ku Tai, Mark W. Albers, Donald P. McDonnell, Hong Chang, Stuart L. Schreiber, Lee E. Faber, Biochemistry, 1994, 33, 10666-10671. download pdf
189. "Specific Inhibition of Formation of Transcription Complexes by the Calicheamicin Oligosaccharide: A Paradigm for the Development of Transcriptional Antagonists" Steffan N. Ho, Serge H. Boyer, Stuart L. Schreiber, Samuel J. Danishefsky, Gerald R. Crabtree, Proc. Natl. Acad. Sci., USA, 1994, 91, 9203-9207. download pdf
190. "Proximity vs Allostery: The Role of Regulated Protein Dimerization in Biology" David J. Austin, Gerald R. Crabtree, Stuart L. Schreiber, Chem. & Biol., 1994, 1, 131-136. download pdf
191. "Mechanistic Studies of a Signaling Pathway Activated by the Organic Dimerizer FK1012" Martin N. Pruschy, David M. Spencer, Tarun M. Kapoor, Hiroshi Miyake, Gerald R. Crabtree, Stuart L. Schreiber, Chem. & Biol., 1994, 1, 163-172. download pdf
192. "Two Binding Orientations for Peptides to Src SH3 Domain: Development of a General Model for SH3-Ligand Interactions" Sibo Feng, James K. Chen, Hongtao Yu, Julian A. Simon, Stuart L. Schreiber, Science, 1994, 266, 1241-1247. download pdf
193. "Acceleration of the Dess-Martin Oxidation by Water" Stephanie D. Meyer, Stuart L. Schreiber, J. Org. Chem., 1994, 59, 7549-7552. download pdf
194. "Evidence for Protein Phosphatase 1 and 2A Regulation of K+ Channels in Two Types of Leaf Cells" Weiwei Li, Sheng Luan, Stuart L. Schreiber, Sarah M. Assmann, Plant Physiology, 1994, 106, 957-961. download pdf
195. "Cyclic AMP Stimulates Channel Activity in Mesophyll Cells of Vicia faba L." Weiwei Li, Sheng Luan, Stuart L. Schreiber, Sarah M. Assmann, Plant Physiology, 1994, 106, 963-970. download pdf
196. "Stereochemical and Conformational Effects on the Cycloaromatization of Dynemicin A-Related Molecules" Daniel Elbaum, John A. Porco, Jr., Thomas J. Stout, Jon Clardy, Stuart L. Schreiber, J. Am. Chem. Soc., 1995, 117, 211-225. download pdf
197. "Grb2 SH3 binding to peptides from Sos: Evaluation of a General Model for SH3-Ligand Interactions" Julian A Simon, Stuart L Schreiber, Chemistry & Biology, 1995, 2, 53-60. download pdf
198. "Inhibition of Proteasome Activities and Subunit-Specific Amino-Terminal Threonine Modification by Lactacystin" Gabriel Fenteany, Robert F. Standaert, William S. Lane, Soongyu Choi, E. J. Corey, Stuart L. Schreiber, Science, 1995, 268, 726-731. download pdf
199. "So wie ein Zahnrad und eine Schraube ineinandergreifen" James K. Chen, Stuart L. Schreiber, Angew Chemie, 1995, 107, 1041-1058.
200. "Combinatorial Synthesis and Multidimensional NMR Spectroscopy: An Approach to Understanding Protein-Ligand Interactions" James K. Chen, Stuart L. Schreiber, Angew Chemie, Int. Ed. Eng., 1995, 34, 953-969. download pdf
201. "Identification of an 11-kDa FKBP12-Rapamycin Binding Domain Within the 289-kDa FKBP12-Rapamycin-Associated Protein and Characterization of a Critical Serine Residue" Jie Chen, Xiao-Feng Zheng, Eric J. Brown, Stuart L. Schreiber, Proc. Natl. Acad. Sci. USA, 1995, 92, 4947-4951. download pdf
202. "A Tricyclic Ring System Replaces the Variable Regions of Peptides Presented by Three Alleles of MHC Class I Molecules" Gregory A. Weiss, Edward J. Collins, David N. Garboczi, Don C. Wiley, Stuart L. Schreiber, Chemistry & Biology, 1995, 2, 401-407. download pdf
203. "TOR Kinase Domains are Required for Two Distinct Functions, Only One of Which is Inhibited by Rapamycin" Xiao-Feng Zheng, David Fiorentino, Jie Chen, Gerald R. Crabtree, Stuart L. Schreiber, Cell, 1995, 82, 121-130. download pdf
204. "Synthesis and Cellular Characterization of the Detransformation Agent, (-)-Depudecin" Junichi Shimada, Ho Jeong Kwon, Masaya Sawamura, Stuart L. Schreiber, Chemistry & Biology, 1995, 2, 517-525. download pdf
205. "Cloning, Zn2+ Binding, and Structural Characterization of the Guanine Nucleotide Exchange factor Human Mss4" Hongtao Yu, Stuart L. Schreiber, Biochemistry, 1995, 34, 9103-9110. download pdf
206. "Structure of a Guanine Nucleotide-Exchange Factor Human Mss4 and Identification of its Target Rab-Interacting Surface" Hongtao Yu, Stuart L. Schreiber, Nature, 1995, 376, 788-791. download pdf
207. "The Enantiospecific Total Synthesis of the Protein Phosphatase Inhibitor Motuporin" Robert J. Valentekovich, Stuart L. Schreiber, J. Am. Chem. Soc., 1995, 117, 9069-9070. download pdf
208. "A General Strategy for Producing Conditional Alleles of Src-Like Tyrosine Kinases" David M. Spencer, Isabella Graef, David J. Austin, Stuart L. Schreiber, Gerald R. Crabtree, Proc. Natl. Acad. Sci. USA, 1995, 92, 9805-9809. download pdf
209. "Signal Transduction in T Lymphocytes Using a Conditional Allele of Sos" Leslie J. Holsinger, David M. Spencer, David J. Austin, Stuart L. Schreiber, Gerald R. Crabtree, Proc. Natl. Acad. Sci. USA, 1995, 92, 9810-9814. download pdf
210. "Structure-Function Analysis of SH3 Domains: SH3 Binding Specificity Altered by Single Amino Acid Substitutions" Zhigang Weng, Richard J. Rickles, Sibo Feng, Stephane Richard, Andrey S. Shaw, Stuart L. Schreiber, Joan S. Brugge, Mol. Cell. Biol., 1995, 15, 5627-5634. download pdf
211. "Control of p70 S6 Kinase by Kinase Activity of FRAP in vivo" Eric J. Brown, Peter Beal, Curtis T. Keith, Jie Chen, Tae Bum Shin, Stuart L. Schreiber, Nature, 1995, 377, 441-446. download pdf
212. "PIK-related Kinases: DNA Repair, Recombination, and Cell Cycle Checkpoints" Curtis T. Keith, Stuart L. Schreiber, Science, 1995, 270, 50-51. download pdf
213. "Rational Design of Orthogonal Receptor-Ligand Combinations" Peter J. Belshaw, Joseph Schoepfer, Karen Liu, Kim Morrison, Stuart L. Schreiber, Angew. Chem., Int. Ed. Eng., 1995, 34, 2129-2132. download pdf
214. "Specific Interactions Outside the Proline-Rich Core of Two Classes of Src Homology 3 Ligands" Sibo Feng, Chiyoshi Kasahara, Richard J. Rickles, Stuart L. Schreiber, Proc. Natl. Acad. Sci. USA, 1995, 92, 12408-12415. download pdf
215. "Protein Structure-Based Combinatorial Chemistry: Discovery of Non-Peptide Binding Elements to Src SH3 Domain" Andrew P. Combs, Tarun M. Kapoor, Sibo Feng, James K. Chen, Lygia F. Daude Snow, Stuart L. Schreiber, J. Am. Chem. Soc., 1996, 118, 287-288. download pdf
216. "Structure of the Human 25 kDa FK506 Binding Protein Complexed with Rapamycin" Jun Liang, Deborah T. Hung, Stuart L. Schreiber, Jon Clardy, J. Am. Chem. Soc., 1996, 118, 1231-1232. download pdf
217. "cDNA Cloning and Gene Mapping of a Candidate Human Cell Cycle Checkpoint Protein" Karlene A. Cimprich, Tae Bum Shin, Curtis T. Keith, Stuart L. Schreiber, Proc. Natl. Acad. Sci. U.S.A, 1996, 93, 2850-2855. download pdf
218. "A Mammalian Histone Deacetylase Related to the Yeast Transcriptional Regulator Rpd3p" Jack Taunton, Christian A. Hassig, Stuart L. Schreiber, Science, 1996, 272, 408-411. download pdf
219. "(+)-Discodermolide Binds to Microtubules in Stoichiometric Ratio to Tubulin Dimers, Blocks Taxol Binding and Results in Mitotic Arrest" Deborah T. Hung, Jie Chen, Stuart L. Schreiber, Chemistry & Biology, 1996, 3, 287-293. download pdf
220. "Crystal Structure of PI3K SH3 Domain at 2.0 Angstrom Resolution" Jun Liang, James K. Chen, Stuart L. Schreiber, Jon Clardy, J. Mol. Biol., 1996, 257, 632-643. download pdf
221. "Didemnin Binds to the Protein Palmitoyl Thioesterase Responsible for Infantile Neuronal Ceroid Lipofuscinosis" Craig M. Crews, William S. Lane, Stuart L. Schreiber, Proc. Natl. Acad. Sci., U.S.A., 1996, 93, 4316-4319. download pdf
222. "Controlling Protein Association and Subcellular Localization with a Synthetic Ligand that Induces Heterodimerization of Proteins" Peter J. Belshaw, Steffan Ho, Gerald R. Crabtree, Stuart L. Schreiber, Proc. Natl. Acad. Sci. U.S.A., 1996, 93, 4604-4607. download pdf
223. "Functional Analysis of Fas Signaling in vivo Using Synthetic Dimerizers" David Spencer, Pete Belshaw, Lei Chen, Steffan Ho, Filippo Randazzo, Gerald R. Crabtree, Stuart L. Schreiber, Curr. Biol., 1996, 6, 839-848. download pdf
224. "Structure of the FKBP12-Rapamycin Complex Interacting with Binding Domain of Human FRAP" Jungwon Choi, Jie Chen, Stuart L. Schreiber, Jon Clardy, Science, 1996, 273, 239-242. download pdf
225. "Molecular Characterization of an FKBP-Type Immunophilin From Higher Plants" Sheng Luan, Jorg Kudla, Wilhelm Gruissem, Stuart L. Schreiber, Proc. Natl. Acad. Sci. USA, 1996, 93, 6964-6969. download pdf
226. "Understanding and Controlling the Cell Cycle with Natural Products" Deborah T. Hung, Timothy F. Jamison, Stuart L. Schreiber, Chemistry & Biology, 1996, 3, 623-640. download pdf
227. "Molecular Basis for the Binding of SH3 Ligands with Non-Peptide Elements Identified by Combinatorial Syntheisis" Sibo Feng, Tarun Kapoor, Fumiyuki Shirai, Andrew P. Combs, Stuart L. Schreiber, Chemistry & Biology, 1996, 3, 661-670. download pdf
228. "A Signaling Pathway to Translational Control" Eric J. Brown, Stuart L. Schreiber, Cell, 1996, 86, 517-520. download pdf
229. "Dimeric Ligands Define a Role for Transcriptional Activation Domains in Reinitiation" Steffan N. Ho, Stephen R. Biggar, David M. Spencer, Stuart L. Schreiber, Gerald R. Crabtree, Nature, 1996, 382, 822-826. download pdf
230. "Covalent HLA-B27/Peptide Complex Induced by Specific Recognition of an Aziridine Mimic of Arginine" Gregory A. Weiss, Robert J. Valentekovich, Edward J. Collins, David N. Garboczi, William S. Lane, Stuart L. Schreiber, Don C. Wiley, Proc. Natl. Acad. Sci., U.S.A., 1996, 93, 10945-10948. download pdf
231. "Controlling Programmed Cell Death with a Cyclophilin-Cyclosporin-Based Chemical Inducer of dimerization" Peter J. Belshaw, Gerald R. Crabtree, Stuart L. Schreiber, Chemistry & Biology, 1996, 3, 731-738. download pdf
232. "Structure of SH3 Domains and Recognition by Ligands" Satoshi Koyama, Stuart L. Schreiber, Cell Technology, 1996, 15, 584-592.
233. "Synthesis of Natural and Modified Trapoxins, Useful Reagents for Exploring the Histone Deacetylase Function" Jack Taunton, Jon L. Collins, Stuart L. Schreiber, J. Am. Chem. Soc., 1996, 118, 10412-10422. download pdf
234. "Three-Part Intervention: Intracellular Signaling and induced Dimerization" Gerald R. Crabtree, Stuart L. Schreiber, Trends in Biochem. Sci., 1996, 21, 418-422. download pdf
235. "Syntheses of Discodermolides Useful for Investigating Microtubule Binding and Stabilization" Deborah T. Hung, Jennie B. Nerenberg, Stuart L. Schreiber, J. Am. Chem. Soc., 1996, 118, 11054-11080. download pdf
236. "Specific Inhibition of the Chymotrypsin-Like Activity of the Proteasome induces a Biopolar Morphology in Neuroblastoma Cells" Gabriel Fenteany, Stuart L. Schreiber, Chemistry & Biology, 1996, 3, 905-912. download pdf
237. "Specific Triggering of the Fas Signal Transduction Pathway in Normal Human Keratinocytes" Rachel A Freiberg, David M. Spencer, Keith Choate, Peter D. Peng, Stuart L. Schreiber, Gerald R. Crabtree, Paul A. Khavari, J. Biol. Chem., 1996, 271, 31666-31669. download pdf
238. "Crystallization and Preliminary X-ray Analysis of Twinned Crystals of a Chimeric FK506 Binding Protein 12 and 13 Complexed with FK506" Jiang Liang, Steve Ealick, C. Nielsen, Stuart L. Schreiber, Jon Clardy, Acta Cryst., 1996, D52, 207-210. download pdf
239. "Regulatory Intramolecular Association in a Tyrosine Kinase of the Tec Family" Amy Hamilton Andreotti, Stephen C. Bunnel, Sibo Feng, Leslie Berg, Stuart L. Schreiber, Nature, 1997, 385, 93-97. download pdf
240. "Immunophilins, Ligands, and the Control of Signal Transduction" Stuart L. Schreiber, Gerald Crabtree, Harvey Society Lectures, 1997, 89, 373-380.
241. "Fas signal transduction triggers either proliferation or apoptosis in human fibroblasts" Rachel A. Freiberg, David M. Spencer, Keith A. Choate, Duh HJ, Stuart L. Schreiber, Gerald R. Crabtree, Paul A. Khavari, J. Invest. Dermatol., 1997, 108, 215-219.
242. "Cell-Specific Calcineurin Inhibition by a Modified Cyclosporin" Peter J. Belshaw, Stuart L. Schreiber, J. Am. Chem. Soc., 1997, 119, 1805-1806. download pdf
243. "Target of Rapamycin Proteins and Their Kinase Activities are Required for Meiosis" Xiao-Feng Steven Zheng, Stuart L. Schreiber, Proc. Natl. Acad. Sci. U.S.A., 1997, 94, 3070-3075. download pdf
244. "Histone Deacetylase Activity is Required for Full Transcriptional Repression by mSin3A" Christian A. Hassig, Tracey C. Fleischer, Andrew N. Billin, Stuart L. Schreiber, Donald E. Ayer, Cell, 1997, 89, 341-347. download pdf
245. "Nuclear Receptor Repression Mediated by a Complex Containing SMRT, mSin3A and Histone Deacetylase" Laszlo Nagy, Hung-Ying Kao, Debabrata Chakravarti, Richard J. Lin, Christian A. Hassig, Donald E. Ayer, Stuart L. Schreiber, Ronald M. Evans, Cell, 1997, 89, 373-380. download pdf
246. "Tandem Use of Cobalt-Mediated Reactions to Synthesize (+)-Epoxydictymene, a Diterpene Containing a trans-Fused 5-5 Ring System" Timothy F. Jamison, Soroosh Shambayati, William E. Crowe, Stuart L. Schreiber, J. Am. Chem. Soc., 1997, 119, 4353-4363. download pdf
247. "Single-Step Syntheses of Cell Permeable Protein Dimerizers that Activate Signal Transduction and Gene Expression" Steven T. Diver, Stuart L. Schreiber, J. Am. Chem. Soc., 1997, 119, 5106-5109. download pdf
248. "Inducible Gene Expression and Protein Translocation Using Non-Toxic Ligands Identified by a Mammalian Three-Hybrid Screen" Stephen D. Liberles, Steven T. Diver, David J. Austin, Stuart L. Schreiber, Proc. Natl. Acad. Sci. U.S.A., 1997, 94, 7825-7830. download pdf
249. "Proximity and orientation underlie signaling by the non-receptor tyrosine kinase ZAP70" Isabella A. Graef, Leslie J. Holsinger, Steve Diver, Stuart L. Schreiber, Gerald R. Crabtree, EMBO J., 1997, 16, 5618-5628. download pdf
250. "Nuclear Histone Acetylases and Deacetylases and Transcriptional Regulation: HATs Off to HDACs" Christian A. Hassig, Stuart L. Schreiber, Curr. Opinion in Chem. Biol., 1997, 1, 300-308. download pdf
251. "Enantiomeric Binding Elements Interacting at the Same Site of a SH3 Protein Receptor" Sibo Feng, Stuart L. Schreiber, J. Am. Chem. Soc., 1997, 119, 10873-10874. download pdf
252. "Fiber-derived Butyrate and the Prevention of Colon Cancer" Christian A. Hassig, Jeffrey K. Tong, Stuart L. Schreiber, Chemistry & Biology, 1997, 4, 783-789. download pdf
253. "A Yeast Genetic System for Selecting Small Molecule Inhibitors of Protein-Protein Interactions in Nanodroplets" Jing Huang and Stuart L. Schreiber, Proc. Natl. Acad. Sci. U.S.A., 1997, 94, 13396-13401. download pdf
254. "Small molecule-dependent genetic selection in stochastic nanodroplets as a means to detect protein-ligand interactions on a large scale" Allen Borchardt, Stephen D. Liberles, Stephen R. Biggar, Gerald R. Crabtree, Stuart L. Schreiber, Chemistry & Biology, 1997, 4, 961-968. download pdf
255. "Miniaturized arrayed assay format for detecting small molecule-protein interactions in cells" Angie You, Rebecca J. Jackman, George M. Whitesides, Stuart L. Schreiber, Chemistry & Biology, 1997, 4, 969-975. download pdf
256. "Small Molecule Control of Insulin and PDGF Receptor Signaling and the Role of Membrane Attachment" Jian-xin Yang, Karen Symes, Mark Mercola, Stuart L. Schreiber, Curr. Biol., 1997, 11-18. download pdf
257. "Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints" William A. Cliby, Christopher J. Roberts, Karlene A. Cimprich, Cheri M. Stringer, John R. Lamb, Stuart L. Schreiber, Stephen H. Friend EMBO J, 1998, 159-169. download pdf
258. "Exploring the Specificity Pockets of Two Homologous SH3 Domains Using Structure-Based, Split-Pool Synthesis and Affinity-Based Selection" Tarun Kapoor, Amy Hamilton Andreotti, Stuart L. Schreiber, J. Am. Chem. Soc., 1998, 23-29. download pdf
259. "Exploring the Leucine-Proline-Binding Pocket of the Src SH3 Domain Using Structure-Based, Split-Pool Synthesis and Affinity-Based Selection" James P. Morken, Tarun M. Kapoor, Sibo Feng, Fumiyuki Shirai, Stuart L. Schreiber, J. Am. Chem. Soc., 1998, 30-36. download pdf
260. "Depudecin Induces Morphological Reversion of Transformed Fibroblasts via the Inhibition of Histone Deacetylase" Ho Jeong Kwon, Takashi Owa, Christian A. Hassig, Junichi Shimada, Stuart L. Schreiber Proc. Natl. Acad.Sci., U.S.A., 1998, 3356-3361. download pdf
261. "A Role for Histone Deacetylase in HDAC1-Mediated Transcriptional Repression" Christian A. Hassig, Jeffrey K. Tong, Tracey C. Fleischer, Takashi Owa, Phyllis Grable, Donald E. Ayer, Stuart L. Schreiber, Proc. Natl. Acad. Sci., U.S.A., 1998, 3519-3524. download pdf
262. "Translation Control: Connecting Mitogens and the Ribosome" Randall T. Peterson and Stuart L. Schreiber, Curr. Biol., 1998, R248-R250. download pdf
263. "Lactacystin, Proteasome Function, and Cell Fate" Gabriel Fenteany, Stuart L. Schreiber, J. Biol. Chem., 1998, 273, 8545-8548. download pdf
264. "Dimerization as a Regulatory Mechanism in Signal Transduction" Juli D. Klemm, Stuart L. Schreiber, Gerald R. Crabtree, Annual Review of Immunology, William E. Paul, Ed., 1998, 16, 569-592. download pdf
265. "Probing the Role Of Homomeric And Heteromeric Receptor Interactions in TGF-b Signaling Using Small Molecule Dimerizers" Brent R. Stockwell, Stuart L. Schreiber, Curr. Biol., 1998, 8, 761-770. download pdf
266. "a4 Associates with Protein Phosphatases 2A, 4, and 6" Jie Chen, Randall T. Peterson, Stuart L. Schreiber, Biochem. Biophys. Res. Commun., 1998, 247, 827-832. download pdf
267. "TGF-b-signaling with small molecule FKBP12 antagonists that bind myristoylated FKBP12-TGF-b type I receptor fusion proteins" Brent R. Stockwell, Stuart L. Schreiber, Chemistry & Biology, 1998, 5, 385-395. download pdf
268. "Stereoselective Synthesis of Over Two Million Compounds Having Structural Features Both Reminiscent of Natural Products and Compatible with Miniaturized Cell-Based Assays" Derek S. Tan, Michael A. Foley, Matthew D. Shair, Stuart L. Schreiber, J. Am. Chem Soc., 1998, 120, 8565-8566. download pdf
269. "Chemical Genetics Resulting from a Passion for Synthetic Organic Chemistry" Stuart L. Schreiber, Bio Med Chem, 1998, 6, 1127-1152. download pdf
270. "An Acid- and Base-Stable o-Nitrobenzyl Photolabile Linker for Solid Phase Organic Synthesis" Scott M. Sternson and Stuart L. Schreiber, Tetrahedron, 1998, 39, 7451-7454. download pdf
271. "Chromatin Deacetylation by an ATP-Dependent Nucleosome Remodelling Complex" Jeffrey K. Tong, Christian A. Hassig, Gavin R. Schnitzler, Robert E. Kingston, Stuart L. Schreiber, Nature, 1998, 395, 917-921. download pdf
272. "High-Throughput Screening of Small Molecules in Miniaturized Mammalian Cell-Based Assays Involving Post-Translational Modifications" Brent R. Stockwell, Stephen J. Haggarty, and Stuart L. Schreiber, Chemistry & Biology, 1999, 6, 71-83. download pdf
273. "The identification of myriocin-binding proteins" James K. Chen, William S. Lane, and Stuart L. Schreiber, Chemistry & Biology, 1999, 6, 221-235. download pdf
274. "Phthalascidin, a synthetic antitumor agent with potency and mode of action comparable to ecteinascidin 743" Eduardo J. Martinez, Takashi Owa, Stuart L. Schreiber, E. J. Corey, Proc. Natl. Acad. Sci., USA, 1999, 96, 3496-3501. download pdf
275. "Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycin-associated protein" Randall Peterson, Bimal N. Desai, James S. Hardwick, and Stuart L. Schreiber, Proc. Natl. Acad. Sci., USA, 1999, 96, 4438-4442. download pdf
276. "The PIK-related kinases intercept conventional signaling pathways" Finny G. Kuruvilla and Stuart L. Schreiber, Chemistry & Biology, 1999, 6, R129-R136. download pdf
277. "Three proteins define a class of human histone deacetylases related to yeast Hda1p" Christina M. Grozinger, Christian Hassig, and Stuart L. Schreiber, Proc. Natl. Acad. Sci., USA, 1999, 96, 4868-4873. download pdf
278. "Kinase phosphorylation: Keeping it all in the family" Randall T. Peterson, Stuart L. Schreiber, Curr. Biol., 1999, 9, R521-R524. download pdf
279. "Printing Small Molecules as Microarrays and Detecting Protein-Ligand Interactions en Masse" Gavin MacBeath, Angela N. Koehler, Stuart L. Schreiber, J. Am. Chem. Soc., 1999, 121, 7967-7968. download pdf
280. "Synthesis and Preliminary Evaluation of a Library of Polycyclic Small Molecules for Use in Chemical Genetic Assays" Derek S. Tan, Michael A. Foley, Brent R. Stockwell, Matthew D. Shair, Stuart L. Schreiber, J. Am. Chem. Soc., 1999, 121, 9073-9087. download pdf
281. "Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen" Thomas U. Mayer, Tarun M. Kapoor, Stephen J. Haggarty, Randall W. King, Stuart L. Schreiber, Timothy J. Mitchison, Science, 1999, 286, 971-974. download pdf
282. "Selection of gp41-mediated HIV-1 cell entry inhibitors from biased combinatorial libraries" M. Ferrer, Tarun M. Kapoor, Dan Oprian, Stuart L. Schreiber, Stephen C. Harrison, Don C. Wiley, Nature Structural Biology, 1999, 6, 953-960. download pdf
283. "Molecular Association between ATR and Two Components of the Nucleosome Remodeling and Deacetylating Complex, HDAC2 and CHD4" Darby R. Schmidt and Stuart L. Schreiber, Biochemistry, 1999,